Alcohol dehydrogenase (ADH) is in the liver cells, located on human chromosome 12. Its genotype is related to the ability for alcohol metabolism. The World Health Organization (WHO) listed alcohol-converted acetaldehyde as a primary carcinogen in 2007. Excessive use and abuse of alcohol are one of the risk factors for dementia.

After drinking alcohol, there are two primary genes for alcohol metabolism: aldehyde dehydrogenase2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B). The aldehyde dehydrogenase2 (ALDH2) affects the metabolic rate of acetaldehyde in the human body. The genotype of ALDH2 is GG, which will quickly metabolize acetaldehyde into acetic acid, and finally, acetic acid will be decomposed into carbon dioxide and water before being excreted. Suppose the ALDH2 genotypes are AA and GA. In that case, the metabolism of acetaldehyde into acetic acid will slow down. Then, the concentration of acetaldehyde in the body increases and causes blush after drinking | nausea | vomiting, and feeling uncomfortable. The genotype of ADH1B is CC, related to poor alcohol metabolism. Therefore, after drinking, the alcohol concentration increases and leads to dizziness.

An individual only uses genetic analysis to increase information about their own body. In addition, the influence of genes is also caused by environmental factors | diet factors | and life stress factors... Knowing congenital physique (gene) weaknesses early and proper health management is an excellent way to maintain your lifelong.